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NexOnco (CIViC Precision Oncology)

Nexonco是由Nexgene Research开发的MCP服务器,用于快速查询CIViC数据库中的临床证据,支持精准肿瘤学研究。

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README

🚀 Nexonco 临床证据查询工具

Nexonco 由 Nexgene 研究提供,是一个基于 MCP 协议的服务器。它能从 CIViC(临床变体在癌症中的医学解释)数据库中访问临床证据,支持快速、灵活地搜索变异、疾病、药物和表型信息,助力精准肿瘤学研究。

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[![PyPI](https://img.shields.io/badge/PyPI-nexonco--mcp-000000.svg?style=for-the-badge&logo=pypi&labelColor=000)](https://pypi.org/project/nexonco-mcp) [![NANDA](https://img.shields.io/badge/NANDA-Nexonco-000000.svg?style=for-the-badge&logo=&labelColor=000)](https://ui.nanda-registry.com/servers/c6284608-6bce-4417-a170-da6c1a117616) [![License](https://img.shields.io/badge/License-MIT-000000.svg?style=for-the-badge&logo=github&labelColor=000)](https://github.com/Nexgene-Research/nexonco-mcp/blob/main/LICENSE)

🚀 快速开始

演示

https://github.com/user-attachments/assets/02129685-5ba5-4b90-89e7-9d4a39986210

观看完整视频:此处

安装与配置

依赖项

Python >= 3.6
Jupyter Notebook
requests
pandas

配置步骤

  1. 克隆仓库:
    git clone https://github.com/Nexgene-Research/nexonco-mcp.git
    cd nexonco-mcp
    
  2. 安装依赖项:
    pip install -r requirements.txt
    
  3. 启动服务器:
    python server.py
    

✨ 主要特性

核心功能

  • 实时数据查询:通过 CIViC 数据库获取最新的临床证据。
  • 多条件搜索:支持对变异、疾病、药物和表型的组合查询。
  • 结果可视化:以表格和图表形式展示查询结果,便于分析。

示例用例

# 查询特定药物的疗效
results = query_therapies("Imatinib", "leukemia")
print(results)

📚 详细文档

使用说明

输入格式

{
  "query": {
    "therapy": "Imatinib",
    "disease": "leukemia"
  },
  "options": {
    "include": ["evidence_level", "clinical_significance"]
  }
}

输出格式

[
  {
    "therapy": "Imatinib",
    "disease": "leukemia",
    "evidence_level": "Level 1",
    "clinical_significance": "Effective"
  },
  ...
]

示例查询

查询示例

  • 问题:哪些疗法与胰腺癌证据相关?
  • 查询代码
    results = query_therapies(disease="pancreatic cancer")
    print(results)
    

📄 许可证

本项目采用 MIT 许可证,具体条款请参见 LICENSE 文件。

⚠️ 重要提示

本工具仅供研究用途。它不能替代专业医疗建议、诊断或治疗。

👥 贡献者

help

Runtime guide

cloud

Hosted runtime

Hosted servers run from a provider-managed environment. You usually connect the MCP client to the hosted endpoint or follow the provider's authorization flow, without keeping a local process alive

  1. Open provider connection page
  2. Authorize or copy endpoint
  3. Connect from your MCP client
terminal

Local runtime / other methods

Local servers run on your own machine or infrastructure. You normally copy the server_config into your MCP client, install the required package, and provide env variables from env_schema when needed

  1. Copy server_config
  2. Install required package
  3. Fill env variables and restart client