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Building AI agents and assistants with Convex. Use when implementing chat interfaces, AI assistants, tool-calling agents, RAG (retrieval-augmented generation), conversation threads, or integrating LLM…
On-device AI with Apple FoundationModels framework: text generation, streaming responses, structured output with @Generable. Use when adding on-device AI features, text generation, or ML-powered conte…
Search memory — sends Huginn (quick grep) first, then Munin (deep agent search) if needed
Comprehensive guide to Claude Opus 4.5, Anthropic's most intelligent model with effort parameter for reasoning control. Covers model capabilities, benchmarks, effort levels (high/medium/low), hybrid r…
Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating …
Structure prediction using Chai-1, a foundation model for molecular structure. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting p…
Binder design ranking using ipSAE (interprotein Score from Aligned Errors). Use this skill when: (1) Ranking binder designs for experimental testing, (2) Filtering BindCraft or RFdiffusion outputs, (3…
As a proxy engineer, operate using evaluation-priority execution, decomposition, and cost-aware model routing.
On-device translation: Translation framework, system translation sheet, TranslationSession API, language detection. Use when adding text translation, language switching, or on-device ML translation fe…
AI-powered prompt refinement and improvement using the Promptheus MCP server. Use this skill whenever the user asks to refine, improve, rewrite, or optimize a prompt. Trigger phrases include "refine t…
Manage and compact context for long sessions. Use when context is filling up, creating handoff summaries, optimizing context usage, or preparing for session continuation.
Process multimodal inputs (images, video, audio, PDFs) with Gemini 3 Pro. Covers image understanding, video analysis, audio processing, document extraction, media resolution control, OCR, and token op…
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding …
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (…
To solve the context issues of sub-agents, a pattern of gradually refining context acquisition
Use this skill when the user asks to "humanize this text", "make this sound less like AI", "fix AI writing patterns", "make this more natural", "rewrite to sound human", or mentions AI-sounding text, …
Human-in-the-loop interaction patterns for ASC operations. Use when asking the user for metadata, settings, or confirmations during App Store Connect workflows.
Use when implementing OCI GenAI inference APIs, debugging rate limit (429) or token limit (400) errors, selecting between command-r vs command-r-plus, handling PHI/PII in prompts, or optimizing GenAI …
Analyze context and decide on continuation via Stop hook. Use when determining if work should continue, analyzing completion status, making continuation decisions, or implementing the Two-Claude patte…
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusi…
End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using diff…
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation prop…
Design and optimize the action space, tool definitions, and observation formats for AI agents to improve completion rates.
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