bio-virtual-screening
Performs structure-based virtual screening using AutoDock Vina 1.2 for molecular docking. Prepares receptor PDBQT files, generates ligand conformers, defines binding site boxes, and ranks compounds by…
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Performs structure-based virtual screening using AutoDock Vina 1.2 for molecular docking. Prepares receptor PDBQT files, generates ligand conformers, defines binding site boxes, and ranks compounds by…
Predict protein-coding genes in eukaryotic genomes using BRAKER3 for combined RNA-seq and protein evidence, or GALBA for protein-only evidence. Runs Augustus with trained parameters for accurate gene …
Find marker genes and annotate cell types in single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for differential expression between clusters, identifying cluster-specific markers, scoring g…
End-to-end biomarker discovery workflow from expression data to validated biomarker panels. Covers feature selection with Boruta/LASSO, classifier training with nested CV, and SHAP interpretation. Use…
Fetch and summarize a web page
Sirv REST API integration for image and file management. Use when working with Sirv CDN, uploading/downloading files to Sirv, managing image metadata, searching files, creating 360 spins, converting v…
Generate images with Pruna P-Image models via inference.sh CLI. Models: P-Image, P-Image-LoRA, P-Image-Edit, P-Image-Edit-LoRA. Capabilities: text-to-image, image editing, LoRA styles, multi-image com…
When the user wants to apply computer vision in warehouses, detect defects, track packages, count inventory, or automate visual inspection. Also use when the user mentions "computer vision," "image re…
Detect m6A modifications from Oxford Nanopore direct RNA sequencing using m6Anet. Use when analyzing epitranscriptomic modifications from long-read RNA data without immunoprecipitation.
Selects informative features for biomarker discovery using Boruta all-relevant selection, mRMR minimum redundancy, and LASSO regularization. Use when identifying biomarkers from high-dimensional omics…
Analyze multi-modal single-cell data (CITE-seq, Multiome, spatial). Use when working with data that measures multiple modalities per cell like RNA + protein or RNA + ATAC. Use when analyzing CITE-seq,…
End-to-end flow cytometry workflow from FCS files to differential analysis. Orchestrates compensation, transformation, gating/clustering, and statistical testing with CATALYST/diffcyt. Use when proces…
This skill should be used when the user asks to "research a topic", "run-research", "last30", "what's happening with X", "what are people saying about X", "find the best X", "X prompts", "latest on X"…
Guide for using Sirv AI Studio (www.sirv.studio), an AI-powered image and video processing platform. Use when working with product images, background removal, image upscaling, AI generation, video cre…
Use yt-dlp to download YouTube videos, audio, or subtitles. Use when user wants to download video, download YouTube, youtube download, download YouTube, download Bilibili, bilibili download.
When the user wants to apply NLP to supply chain, extract information from documents, analyze supplier communications, classify items, or process unstructured text. Also use when the user mentions "na…
Assign GO terms, KEGG orthologs, Pfam domains, and EC numbers to predicted proteins using eggNOG-mapper and InterProScan. Produces functional summaries for downstream pathway and enrichment analysis. …
Exports publication-ready figures in various formats with proper resolution, sizing, and typography. Use when preparing figures for journal submission, creating vector graphics for presentations, or e…
Detects circadian and ultradian rhythms in time-series omics data using CosinorPy cosinor models, MetaCycle (JTK_CYCLE, ARSER), and RAIN non-parametric tests. Fits cosine models to estimate phase and …
Build LLM-powered applications and pipelines using proven methodology - task-model fit analysis, pipeline architecture, structured outputs, file-based state, and cost estimation. Use when building AI …
Article writing and draft management tool. Activate for these exact commands: "show my drafts", "show my archive", "show my articles", "list my writing styles", "create a new article style", "edit sty…
Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. N…
Systematically analyze existing media to extract transferable elements for new settings. Use when adapting TV, film, or games to fiction, translating tropes across genres, or transforming genre elemen…
Local-first RAG memory system for AI agents. Progressive Disclosure search, Auto-Capture from sessions, Brain directories for per-project context, injection defense.