claim-strength-calibrator
Calibrates manuscript claim strength so wording matches the actual evidence level, study design, and validation status.
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Calibrates manuscript claim strength so wording matches the actual evidence level, study design, and validation status.
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Datadog CLI for searching logs, querying metrics, tracing requests, and managing dashboards. Use this when debugging production issues or working with Datadog observability.
Use when screening differentially expressed genes from a bulk expression matrix between two user-specified groups, producing DEG tables, a volcano plot, and a clustered heatmap. Triggers include DEG a…
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Download supplementary data files, series matrices, and raw FASTQ links from NCBI GEO for a given GSE series or GSM sample accession.
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Use when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk distribution plots, heatmap, an…
Set up a compute environment on a remote provider so Claude Science jobs can run there. Covers direct SSH/conda hosts, Slurm clusters, container-via-bridge runners, and managed-API providers (Modal, G…
Drafts journal-ready cover letters for manuscript submission. Use when preparing a submission package, communicating the manuscript's contributions and journal fit to editors, or tailoring the novelty…
Use when evaluating the clinical utility of a binary prediction model from a single clinical CSV file by fitting a logistic decision-curve model, plotting decision and clinical-impact curves, and expo…
Analyzes clinical diagnostic accuracy studies for bias using the QUADAS-2 tool. Use when Claude needs to assess the quality, risk of bias, or applicability of diagnostic accuracy studies (e.g., \"Asse…
Composes a Discussion around key findings, mechanisms, clinical relevance, and limitations. Use when writing or improving a Discussion section for any biomedical manuscript — including interpreting re…
Download raw sequencing data from NCBI SRA as FASTQ files using prefetch and fasterq-dump, with support for single accessions, batch lists, and BioProject expansion.
Use this skill to compute ESTIMATE immune-related microenvironment scores from a bulk expression matrix, generate an ESTIMATE score heatmap, and optionally generate group-wise ESTIMATE score boxplots …
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Checks consistency across title, abstract, methods, results, figures, tables, and supplements to identify internal contradictions and version drift in biomedical manuscripts.
Create, configure, and maintain custom agent profiles and author new skills via the `repl` tool. Use when the user wants to create an agent profile, build a custom agent, modify agent capabilities, at…
Use when building a decision tree model in R and generating feature importance ranking outputs. Supports classification and regression, automatic task detection, parameter validation, model evaluation…
Use when analyzing bulk RNA-seq or microarray expression data to identify differentially expressed genes between two biological groups (case vs control), with volcano plots and heatmap visualization. …
Download files from the NCI Genomic Data Commons (GDC) using the GDC Data Transfer Tool and REST API, supporting both open-access and controlled-access data.
Use when selecting predictive genes or other molecular features from bulk expression matrices for binary case-vs-control classification with elastic net logistic regression, including coefficient path…
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