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Senior-level code review specifically for scientific/research code in bioinformatics, medical imaging, ML/DL pipelines, and statistical software. Covers correctness (numerical stability, data leakage,…
Create a timestamped research-session progress log that records completed work, evidence, decisions, and next steps. Use when closing or checkpointing substantive project work that needs a durable chr…
Multi-cloud orchestration for ML workloads with automatic cost optimization. Use when you need to run training or batch jobs across multiple clouds, leverage spot instances with auto-recovery, or opti…
Systematic review of adverse effects per Cochrane Handbook Ch 19. Use when the review includes harm outcomes, rare events, zero-event studies, or safety-focused synthesis. Includes different study des…
Integrate economic evidence into SRs per Cochrane Handbook Ch 20 + 20.S. Use when the review includes cost-effectiveness, cost-utility, or cost-benefit analyses. CHEERS 2022 compliance, CHEC-list crit…
Structured interpretation of SR results per Cochrane Handbook Ch 15. Use when the user needs to interpret meta-analysis results, compute NNT, re-express SMDs, assess applicability, or draw conclusions…
Systematic review Phase 1 — PICO development and topic formulation for EM/critical care. Use when the user wants to define their research question, build a PICO(S) framework, identify eligibility crit…
Handle non-standard RCT designs in SRs per Cochrane Handbook Ch 23. Use when included studies include cluster RCTs, crossover trials, stepped-wedge designs, equivalence/non-inferiority trials, or mult…
Sensitivity analysis frameworks and assumption-testing methods
Simple Preference Optimization for LLM alignment. Reference-free alternative to DPO with better performance (+6.4 points on AlpacaEval 2.0). No reference model needed, more efficient than DPO. Use for…
Provides guidance for LLM post-training with RL using slime, a Megatron+SGLang framework. Use when training GLM models, implementing custom data generation workflows, or needing tight Megatron-LM inte…
Phase 0 — Topic brainstorming and research gap exploration for EM/critical care SRs. Use when the user has a broad topic area but no specific question yet. Guides through landscape scanning, gap ident…
Systematic review Phase 5 — Data extraction form design, execution, missing data handling, and outcome harmonization for EM/critical care SRs. Use when the user needs an extraction form, help with mis…
Non-meta-analytic synthesis methods per Cochrane Handbook Ch 12. Use when meta-analysis is not possible and alternative synthesis is needed. Three acceptable methods: summarizing effect estimates, com…
Prospective approaches to accumulating evidence per Cochrane Handbook Ch 22. Use when the user needs prospective meta-analysis (PMA), trial sequential analysis (TSA), cumulative meta-analysis, or livi…
Systematic review Phase 6 — Risk of bias assessment using RoB 2.0, ROBINS-I, QUADAS-2, QUIPS, and JBI tools for EM/critical care SRs. Use when the user needs to assess study quality, select the correc…
Language-independent tokenizer treating text as raw Unicode. Supports BPE and Unigram algorithms. Fast (50k sentences/sec), lightweight (6MB memory), deterministic vocabulary. Used by T5, ALBERT, XLNe…
Design and implementation of comprehensive simulation studies
Provides guidance for training and analyzing Sparse Autoencoders (SAEs) using SAELens to decompose neural network activations into interpretable features. Use when discovering interpretable features, …
Systematic reviews of complex interventions per Cochrane Handbook Ch 17. Use when the intervention has multiple interacting components, is context-dependent, or involves behaviour change. Logic models…
Systematic review Phase 8 — GRADE assessment and Summary of Findings for EM/critical care SRs. Use when the user needs to rate certainty of evidence, generate a Summary of Findings (SoF) table, apply …
Handle patient-reported outcomes (PROs) in systematic reviews per Cochrane Handbook Ch 18. Use when included studies use patient-reported outcomes like quality of life, pain, function, or symptom scal…
Systematic review Phase 2 — Protocol writing and PROSPERO registration for EM/critical care SRs. Use when the user needs a full PRISMA-P-compliant protocol, PROSPERO field mapping, timeline estimation…
Systematic review Phase 3 — Literature search, string construction, database translation, deduplication, and PRISMA-S compliance for EM/critical care SRs. Use when the user needs to build, test, or re…