scrnaseq-cell-type-annotation
Marker-based and reference-based cell type annotation of single-cell RNA-seq clusters using SingleR, Azimuth, or manual curation.
Browse curated skills with source links, package snapshots, README assets and install signals in one calm, searchable catalog.
Marker-based and reference-based cell type annotation of single-cell RNA-seq clusters using SingleR, Azimuth, or manual curation.
Single-cell differential expression analysis using Wilcoxon rank-sum tests and pseudobulk approaches with DESeq2 or edgeR.
Search the EMBL-EBI European Nucleotide Archive (ENA) for sequencing studies, runs, samples, and experiments using the ENA Portal REST API.
Search NCBI Datasets for genome assemblies, genes, taxonomy records, and virus genomes using the NCBI Datasets CLI or REST API.
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Converts biomedical table content into clear manuscript or presentation narrative by prioritizing meaningful patterns, contrasts, and interpretation boundaries rather than restating every number.
Create Word-style flowcharts in Graphviz DOT with black/white styling, orthogonal arrows, and clean alignment. Use when converting text or images into flowcharts, refining DOT layout/spacing, enforcin…
Generate feature-barcode count matrices from raw scRNA-seq FASTQ files using Cell Ranger, STARsolo, or alevin-fry.
Multi-sample batch correction and integration of single-cell RNA-seq datasets using Harmony, Seurat CCA/RPCA, or scVI.
Search NCBI Gene Expression Omnibus (GEO) for expression datasets, series, samples, and platforms using E-utilities or the GEO query API.
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Performs quality control on single-cell RNA-seq data (.h5ad or .h5 files) using scverse best practices with MAD-based filtering and comprehensive visualizations. Use when users request QC analysis, fi…
Diagnose, review, and strengthen social-science manuscripts, research designs, literature reviews, grant proposals, thesis chapters, methods sections, revision plans, and submission-readiness decision…
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Normalization, highly variable gene selection, PCA, UMAP, and Leiden/Louvain clustering of single-cell RNA-seq data.
Ambient RNA removal, doublet detection, and cell filtering for single-cell RNA-seq count matrices.
Search CNCB Genome Sequence Archive (GSA) for sequencing runs, experiments, studies, and samples deposited at the China National Center for Bioinformation.
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Structures research progress into focused and actionable slides for lab meetings or project reviews without inventing missing content.
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Optimizes manuscript titles and abstracts for information density, factual accuracy, and submission fit in biomedical research writing.
Review research writing by leaving inline comments on logic, notation, narrative flow, positioning, and editorial impact. Use when Codex needs to annotate a paper or draft with reader-facing comments …