genome-variant-filtering
Filter raw variant calls using GATK VQSR, GATK hard filters, or bcftools expression-based filtering.
Browse curated skills with source links, package snapshots, README assets and install signals in one calm, searchable catalog.
Filter raw variant calls using GATK VQSR, GATK hard filters, or bcftools expression-based filtering.
Drafting and reviewing European fellowship and grant applications (Marie Skłodowska-Curie Actions, Horizon Europe, ERC, EIC). Covers the Excellence/Impact/Implementation triad, gender dimension and se…
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Export PubMed paper(s) to Zotero or save as RIS file. Supports single paper by PMID or batch export from search results. Use when user wants to save papers to their reference manager.
High-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. Overlap, nearest, merge, coverage, complement, subtract for BED/VCF/BAM/GFF intervals. Streaming, cloud-n…
Use this skill whenever a user wants to adopt the scicomp-research-skills framework on an EXISTING project (paper, software library, analysis repo) rather than starting from scratch -- OR when the age…
數學證明撰寫技能 — 從主張提取到 LaTeX 排版的完整證明工作流。當使用者需要撰寫或驗證數學定理、引理、命題的形式證明,或需要推導公式、整理理論分析時,一定要使用此技能。觸發詞包括:數學證明、prove、theorem、lemma、proposition、推導、理論分析、寫 proof、LaTeX 數學、formal proof。適用於機器學習理論、統計學習理論、最佳化等需要嚴謹數學推導的場景…
Comprehensive geospatial science skill covering remote sensing, GIS, spatial analysis, machine learning for earth observation, and 30+ scientific domains. Supports satellite imagery processing (Sentin…
Converts a biomedical study storyline into a graphical abstract and, when direct image capability is available, generates the graphical abstract directly; otherwise it falls back to prompts, Mermaid f…
Parameter-efficient fine-tuning for LLMs using LoRA, QLoRA, and 25+ methods. Use when fine-tuning large models (7B-70B) with limited GPU memory, when you need to train <1% of parameters with minimal a…
Build a traceability manifest linking analysis scripts to inputs, outputs, and manuscript figures or tables. Use when documenting a computational pipeline or locating the source of a reported artefact…
Find full-text download links for a PubMed paper by PMID - DOI, PMC open access, Sci-Hub, and publisher links. Use when user wants to read or download a paper's full text.
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Install or reconcile research-project safety rules and protected folder boundaries for data, code, outputs, and paper sources. Use when a project lacks guardrails or is being migrated into the governe…
Proofread a LaTeX academic paper across eleven language, notation, citation, and consistency categories. Use when the requested task is bounded proofreading rather than substantive rewriting, clarity …
Writes Specific Aims pages for grant applications. Use when drafting or revising the Specific Aims page (NIH R01/R21/R03), NSF Project Summary, or equivalent for any major funding agency. Also trigger…
Expert guidance for GRPO/RL fine-tuning with TRL for reasoning and task-specific model training
Build and analyze phylogenetic trees using MAFFT (multiple alignment), IQ-TREE 2 (maximum likelihood), and FastTree (fast NJ/ML). Visualize with ETE3 or FigTree. For evolutionary analysis, microbial g…
Perform advanced PubMed search with field qualifiers - author, title, journal, MeSH, date range, article type. Constructs proper PubMed query syntax from natural language. Use for precise filtered sea…
Navigate PubMed search result pages or change sort order. Use when user wants to see more results or change ordering.
analyze a professor from google scholar, publication lists, personal websites, lab pages, and field-specific bibliographic databases (e.g., DBLP, PubMed, SSRN, PhilPapers, MathSciNet, arXiv, Scopus) t…
Structured methodology for constructing and verifying mathematical proofs in statistical research
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