AlphaFold Predictor Skill

Purpose

Enable AlphaFold protein structure prediction with confidence assessment and model analysis.

Capabilities

• Structure prediction execution
• pLDDT confidence scoring
• PAE analysis
• Multi-chain complex prediction
• Template-based refinement
• ColabFold integration

Usage Guidelines

• Review pLDDT scores for prediction confidence
• Analyze PAE for domain boundaries
• Predict complexes for multi-protein assemblies
• Use templates when homologs exist
• Validate predictions against experimental data
• Document model versions and parameters

Dependencies

• AlphaFold2
• ColabFold
• RoseTTAFold

Process Integration

• Protein Structure Prediction (protein-structure-prediction)
• Molecular Docking and Virtual Screening (molecular-docking)